Syrian rue, its scientific name is Peganum Harmala. Syrian rue has been a commonly used plant since ancient times. Around 60 AD. Peganum harmala was described by Dioscorides in his “De materia medica”. He says “wild rue mixed with honey, wine, chicken gall, saffron and fennel juice produces mild visions.”
Peganum Harmala belongs to the Nitrariaceae plant family and can reach a height of about 1 meter. In the wild, it often does not exceed 0.3m. The plant has narrow leaves and produces many single white flowers.

The seeds of Peganum Harmala are the most interesting because they contain the alkaloids harmine and harmaline. These alkaloids are very psychoactive and are sometimes used to give other plants more power. Harmala alkaloids are also psychoactive in their own right, it has been reported. They also act as reversible MAO inhibitors (RIMAs) and for that reason Peganum Harmala is used, for example, to activate oral DMT.
Since Peganum Harmala is a MAOI, it is often used to energize other psychedelic plants, enhancing them and prolonging the high. For example, if you take Peganum Harmala with Magic Mushrooms or DMT, the experience will be extended up to 4 hours.
Peganum Harmala can also be used on its own, but this can cause an unpleasant feeling. Anecdotal accounts describe how pure harmala alkaloids from rue can induce psychedelic effects. From visual images with closed eyes to patterns and distortions with open eyes.
Use
There are a number of ways to use Peganum Harmala. The easiest way is to just chew the seeds. You keep them in your mouth for about two minutes. Make sure to chew it well and let the seeds come into contact with your saliva as much as possible before swallowing. Its taste is very bitter, so most people prefer to grind the seeds first. You can swallow the powder or put it in a capsule.There are a number of ways to use Peganum Harmala. The easiest way is to just chew the seeds. You keep them in your mouth for about two minutes. Make sure to chew it well and let the seeds come into contact with your saliva as much as possible before swallowing. Its taste is very bitter, so most people prefer to grind the seeds first. You can swallow the powder or put it in a capsule.